Caspase‐3 Activation Is Not Responsible for Vinblastine‐induced Bcl‐2 Phosphorylation and G2/M Arrest in Human Small Cell Lung Carcinoma Ms‐1 Cells

Vinblastine arrests cells in the G2/M phase of the cell cycle and subsequently induces cell death by apoptosis. We found that treatment of cells with vinblastine induced phosphorylation of Bcl‐2, resulting in the dissociation of Bcl‐2 and Bax. Moreover, vinblastine‐induced apoptosis was suppressed b...

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Detalles Bibliográficos
Autores principales: Tashiro, Etsu, Simizu, Siro, Takada, Minoru, Umezawa, Kazuo, Imoto, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921943/
https://www.ncbi.nlm.nih.gov/pubmed/9818030
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00652.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921943/
https://www.ncbi.nlm.nih.gov/pubmed/9818030
http://dx.doi.org/10.1111/j.1349-7006.1998.tb00652.x

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