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Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized

BACKGROUND: The relationship between cholesterol and prostate cancer has been extensively studied for decades, where high levels of cellular cholesterol are generally associated with cancer progression and less favorable outcomes. However, the role of in vivo cellular cholesterol synthesis in this p...

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Detalles Bibliográficos
Autores principales: Rye, Morten Beck, Bertilsson, Helena, Andersen, Maria K., Rise, Kjersti, Bathen, Tone F., Drabløs, Finn, Tessem, May-Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922022/
https://www.ncbi.nlm.nih.gov/pubmed/29703166
http://dx.doi.org/10.1186/s12885-018-4373-y