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Endogenous ornithine decarboxylase/polyamine system mediated the antagonist role of insulin/PEG-CMCS preconditioning against heart ischemia/reperfusion injury in diabetes mellitus

INTRODUCTION: Insulin has shown antioxidation and cytoprotective effects to decrease heart ischemia/reperfusion injury (HI/RI) in diabetes mellitus (DM), but the role of insulin/poly(ethylene glycol)-carboxymethyl chitosan (PEG-CMCS) on HI/RI in DM is not known. This research explored whether insuli...

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Detalles Bibliográficos
Autores principales: Tong, Fei, Liu, Suhuan, Yan, Bing, Li, Xuejun, Ruan, Shiwei, Yang, Shuyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922236/
https://www.ncbi.nlm.nih.gov/pubmed/29719397
http://dx.doi.org/10.2147/IJN.S160848