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Tumor cell death after electrotransfer of plasmid DNA is associated with cytosolic DNA sensor upregulation
Cytosolic DNA sensors are a subgroup of pattern recognition receptors (PRRs) and are activated by the abnormal presence of the DNA in the cytosol. Their activation leads to the upregulation of pro-inflammatory cytokines and chemokines and can also induce cell death. The presence of cytosolic DNA sen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922346/ https://www.ncbi.nlm.nih.gov/pubmed/29721152 http://dx.doi.org/10.18632/oncotarget.24816 |