Cargando…

Tumor cell death after electrotransfer of plasmid DNA is associated with cytosolic DNA sensor upregulation

Cytosolic DNA sensors are a subgroup of pattern recognition receptors (PRRs) and are activated by the abnormal presence of the DNA in the cytosol. Their activation leads to the upregulation of pro-inflammatory cytokines and chemokines and can also induce cell death. The presence of cytosolic DNA sen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Znidar, Katarina, Bosnjak, Masa, Semenova, Nina, Pakhomova, Olga, Heller, Loree, Cemazar, Maja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper: Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922346/ https://www.ncbi.nlm.nih.gov/pubmed/29721152 http://dx.doi.org/10.18632/oncotarget.24816

Ejemplares similares

Cytosolic DNA Sensor Upregulation Accompanies DNA Electrotransfer in B16.F10 Melanoma Cells
por: Znidar, Katarina, et al.
Publicado: (2016)

Multiple cytosolic DNA sensors bind plasmid DNA after transfection
por: Semenova, Nina, et al.
Publicado: (2019)

Upregulation of DNA Sensors in B16.F10 Melanoma Spheroid Cells After Electrotransfer of pDNA
por: Znidar, Katarina, et al.
Publicado: (2018)

Radiation Induced Upregulation of DNA Sensing Pathways is Cell-Type Dependent and Can Mediate the Off-Target Effects
por: Jesenko, Tanja, et al.
Publicado: (2020)

Electrotransfer of Different Control Plasmids Elicits Different Antitumor Effectiveness in B16.F10 Melanoma
por: Bosnjak, Masa, et al.
Publicado: (2018)

Electrotransfer of single-stranded or double-stranded DNA induces complete regression of palpable B16.F10 mouse melanomas
por: Heller, Loree, et al.
Publicado: (2013)

Evaluation of a Novel Plasmid for Simultaneous Gene Electrotransfer-Mediated Silencing of CD105 and CD146 in Combination with Irradiation
por: Savarin, Monika, et al.
Publicado: (2021)

Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response
por: Kranjc Brezar, Simona, et al.
Publicado: (2020)

Tumor perfusion evaluation using dynamic contrast-enhanced ultrasound after electrochemotherapy and IL-12 plasmid electrotransfer in murine melanoma
por: Brloznik, Maja, et al.
Publicado: (2021)

Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response
por: Savarin, Monika, et al.
Publicado: (2017)

Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects
por: Dolinsek, Tanja, et al.
Publicado: (2015)

Tumor Radiosensitization by Gene Electrotransfer-Mediated Double Targeting of Tumor Vasculature
por: Savarin, Monika, et al.
Publicado: (2023)

Acute Effects of Intratumor DNA Electrotransfer
por: Bhandary, Manya, et al.
Publicado: (2022)

Gene Immunotherapy of Colon Carcinoma with IL-2 and IL-12 Using Gene Electrotransfer
por: Komel, Tilen, et al.
Publicado: (2023)

Antitumor in situ vaccination effect of TNFα and IL-12 plasmid DNA electrotransfer in a murine melanoma model
por: Kamensek, Urska, et al.
Publicado: (2018)

Evaluation of delivery conditions for cutaneous plasmid electrotransfer using a multielectrode array
por: Ferraro, Bernadette, et al.
Publicado: (2010)

Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity
por: Sedlar, Ales, et al.
Publicado: (2012)

Treatment of Skin Tumors with Intratumoral Interleukin 12 Gene Electrotransfer in the Head and Neck Region: A First-in-human Clinical Trial Protocol
por: Groselj, Ales, et al.
Publicado: (2022)

Results of Dynamic Contrast-Enhanced Ultrasound Correlate With Treatment Outcome in Canine Neoplasia Treated With Electrochemotherapy and Interleukin-12 Plasmid Electrotransfer
por: Brloznik, Maja, et al.
Publicado: (2021)

What We Learned about the Feasibility of Gene Electrotransfer for Vaccination on a Model of COVID-19 Vaccine
por: Kamensek, Urska, et al.
Publicado: (2023)

The effectiveness of calcium electroporation combined with gene electrotransfer of a plasmid encoding IL-12 is tumor type-dependent
por: Lisec, Barbara, et al.
Publicado: (2023)

Non-Clinical In Vitro Evaluation of Antibiotic Resistance Gene-Free Plasmids Encoding Human or Murine IL-12 Intended for First-in-Human Clinical Study
por: Kos, Spela, et al.
Publicado: (2021)

In Vivo Molecular Imaging and Histological Analysis of Changes Induced by Electric Pulses Used for Plasmid DNA Electrotransfer to the Skin: A Study in a Dorsal Window Chamber in Mice
por: Markelc, Bostjan, et al.
Publicado: (2012)

Maintenance and gene electrotransfer efficiency of antibiotic resistance gene-free plasmids encoding mouse, canine and human interleukin-12 orthologues
por: Kamensek, Urska, et al.
Publicado: (2022)

Mapping of bionic array electric field focusing in plasmid DNA-based gene electrotransfer
por: Browne, C J, et al.
Publicado: (2016)

Numerical study of gene electrotransfer efficiency based on electroporation volume and electrophoretic movement of plasmid DNA
por: Forjanič, Tadeja, et al.
Publicado: (2018)

A Novel Method for Controlled Gene Expression via Combined Bleomycin and Plasmid DNA Electrotransfer
por: Chopra, Sonam, et al.
Publicado: (2019)

Optimization of Mouse Growth Hormone Plasmid DNA Electrotransfer into Tibialis Cranialis Muscle of “Little” Mice
por: Rosa Lima, Eliana, et al.
Publicado: (2020)

Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer
por: Sersa, Gregor, et al.
Publicado: (2015)

Health‐related quality of life in dogs treated with electrochemotherapy and/or interleukin‐12 gene electrotransfer
por: Milevoj, Nina, et al.
Publicado: (2020)

Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma
por: Sedlar, Ales, et al.
Publicado: (2013)

Gene Electrotransfer of Plasmid with Tissue Specific Promoter Encoding shRNA against Endoglin Exerts Antitumor Efficacy against Murine TS/A Tumors by Vascular Targeted Effects
por: Stimac, Monika, et al.
Publicado: (2015)

Development of Tumor Cell-Based Vaccine with IL-12 Gene Electrotransfer as Adjuvant
por: Remic, Tinkara, et al.
Publicado: (2020)

Comparison of electrically mediated and liposome-complexed plasmid DNA delivery to the skin
por: Heller, Loree C, et al.
Publicado: (2008)

Plasma-activated air mediates plasmid DNA delivery in vivo
por: Edelblute, Chelsea M, et al.
Publicado: (2016)

Optimizing hyaluronidase dose and plasmid DNA delivery greatly improves gene electrotransfer efficiency in rat skeletal muscle
por: Akerstrom, Thorbjorn, et al.
Publicado: (2015)

In vitro and in vivo correlation of skin and cellular responses to nucleic acid delivery
por: Bosnjak, M., et al.
Publicado: (2022)

Gene Electrotransfer of Plasmid-Encoding IL-12 Recruits the M1 Macrophages and Antigen-Presenting Cells Inducing the Eradication of Aggressive B16F10 Murine Melanoma
por: Lampreht Tratar, Ursa, et al.
Publicado: (2017)

Muscle gene electrotransfer is increased by the antioxidant tempol in mice
por: Markelc, B, et al.
Publicado: (2012)

Overcoming the Specific Toxicity of Large Plasmids Electrotransfer in Primary Cells In Vitro
por: Lesueur, Léa L, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_trkf34gg9d3dft072h8par06ek