Differentiation-inducing therapeutic effect of Notch inhibition in reversing malignant transformation of liver normal stem cells via MET

BACKGROUND: Liver cancer stem cells (LCSCs) are the key factors for cancer metastasis, recurrent, and drug resistance. LCSCs are originated from either hepatocytes dedifferentiation or differentiation arresting of liver normal stem cells (LNSCs). Differentiation-inducing therapy is a novel strategy...

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Detalles Bibliográficos
Autores principales: Luo, Hao, Liu, Wei-Hui, Liang, Hong-Yin, Yan, Hong-Tao, Lin, Ning, Li, Dong-Yu, Wang, Tao, Tang, Li-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922363/
https://www.ncbi.nlm.nih.gov/pubmed/29721169
http://dx.doi.org/10.18632/oncotarget.24421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922363/
https://www.ncbi.nlm.nih.gov/pubmed/29721169
http://dx.doi.org/10.18632/oncotarget.24421

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