DNMT1 ablation suppresses tumorigenesis by inhibiting the self-renewal of esophageal cancer stem cells

Cancer stem cells (CSCs) have been isolated from many tumors and considered as the main reason of cancer recurrence and metastasis. DNA methyltransferase 1 (DNMT1) mediates DNA methylation and plays an important role in CSCs maintenance. However, the function of DNMT1 in CSCs of esophageal squamous...

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Detalles Bibliográficos
Autores principales: Teng, Ying, Yu, Xiying, Yuan, Hui, Guo, Liping, Jiang, Wei, Lu, Shih-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922364/
https://www.ncbi.nlm.nih.gov/pubmed/29721170
http://dx.doi.org/10.18632/oncotarget.24116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922364/
https://www.ncbi.nlm.nih.gov/pubmed/29721170
http://dx.doi.org/10.18632/oncotarget.24116

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