Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer

A CMS approved test for lung cancer is based on tumor-only analysis of a targeted 35 gene panel, specifically excluding the use of the patient’s normal germline tissue. However, this tumor-only approach increases the risk of mistakenly identifying germline single nucleotide polymorphisms (SNPs) as s...

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Detalles Bibliográficos
Autores principales: Rabizadeh, Shahrooz, Garner, Chad, Sanborn, John Zachary, Benz, Stephen C., Reddy, Sandeep, Soon-Shiong, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922390/
https://www.ncbi.nlm.nih.gov/pubmed/29721196
http://dx.doi.org/10.18632/oncotarget.24973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922390/
https://www.ncbi.nlm.nih.gov/pubmed/29721196
http://dx.doi.org/10.18632/oncotarget.24973

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