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Comprehensive genomic transcriptomic tumor-normal gene panel analysis for enhanced precision in patients with lung cancer
A CMS approved test for lung cancer is based on tumor-only analysis of a targeted 35 gene panel, specifically excluding the use of the patient’s normal germline tissue. However, this tumor-only approach increases the risk of mistakenly identifying germline single nucleotide polymorphisms (SNPs) as s...
Autores principales: | Rabizadeh, Shahrooz, Garner, Chad, Sanborn, John Zachary, Benz, Stephen C., Reddy, Sandeep, Soon-Shiong, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922390/ https://www.ncbi.nlm.nih.gov/pubmed/29721196 http://dx.doi.org/10.18632/oncotarget.24973 |
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