Backtracked analysis of preleukemic fusion genes and DNA repair foci in umbilical cord blood of children with acute leukemia

The first event in origination of many childhood leukemias is a specific preleukemic fusion gene (PFG) that arises, often in utero, in hematopoietic stem/progenitor cells (HSPC) from misrepaired DNA double strand break (DSB). An immanently elevated level of DSB and impaired apoptosis may contribute...

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Detalles Bibliográficos
Autores principales: Škorvaga, Milan, Durdík, Matúš, Košík, Pavol, Marková, Eva, Holop, Marek, Kubeš, Miroslav, Puškáčová, Judita, Kolenová, Alexandra, Belyaev, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922391/
https://www.ncbi.nlm.nih.gov/pubmed/29721197
http://dx.doi.org/10.18632/oncotarget.24976

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922391/
https://www.ncbi.nlm.nih.gov/pubmed/29721197
http://dx.doi.org/10.18632/oncotarget.24976

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