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Recombinant methioninase combined with doxorubicin (DOX) regresses a DOX-resistant synovial sarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model

Synovial sarcoma (SS) is a recalcitrant subgroup of soft tissue sarcoma (STS). A tumor from a patient with high grade SS from a lower extremity was grown orthotopically in the right biceps femoris muscle of nude mice to establish a patient-derived orthotopic xenograft (PDOX) mouse model. The PDOX mi...

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Detalles Bibliográficos
Autores principales: Igarashi, Kentaro, Kawaguchi, Kei, Li, Shukuan, Han, Qinghong, Tan, Yuying, Gainor, Emily, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Higuchi, Takashi, Oshiro, Hiromichi, Singh, Arun S., Eckardt, Mark A., Nelson, Scott D., Russell, Tara A., Dry, Sarah M., Li, Yunfeng, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922394/
https://www.ncbi.nlm.nih.gov/pubmed/29721200
http://dx.doi.org/10.18632/oncotarget.24996