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Radiotherapy increases plasma levels of tumoral cell-free DNA in non-small cell lung cancer patients

We investigated the plasma levels of tumor-specific cell-free DNA (cfDNA) in 17 stage I–II (early) and IV (advanced) non-small cell lung cancer (NSCLC) patients who underwent radiotherapy. Digital polymerase chain reaction (PCR) and targeted sequencing showed that total and tumor-specific cfDNA leve...

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Detalles Bibliográficos
Autores principales: Kageyama, Shun-ichiro, Nihei, Keiji, Karasawa, Katsuyuki, Sawada, Takeshi, Koizumi, Fumiaki, Yamaguchi, Shigeo, Kato, Shunsuke, Hojo, Hidehiro, Motegi, Atsuhi, Tsuchihara, Katsuya, Akimoto, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922403/
https://www.ncbi.nlm.nih.gov/pubmed/29721209
http://dx.doi.org/10.18632/oncotarget.25053