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Bioanalytical method development and validation of HPLCUV assay for the quantification of SHetA2 in mouse and human plasma: Application to pharmacokinetics study

BACKGROUND: SHetA2 is an oral anticancer agent being investigated for cancer treatment and prevention. The aim of this study was to develop and validate a simple, cost-effective, and sensitive HPLC-UV method for the quantification of SHetA2 in biological samples and to apply the method to pharmacoki...

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Detalles Bibliográficos
Autores principales: Sharma, Ankur, Thavathiru, Elangovan, Benbrook, Doris Mangiaracina, Woo, Sukyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922436/
https://www.ncbi.nlm.nih.gov/pubmed/29708233
http://dx.doi.org/10.7243/2050-120X-6-2