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Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Invasive fungal infections caused by the pathogen Candida albicans have transitioned from a rare curiosity to a major cause of human mortality. This is in part due to the emergence of resistance to the limited number of antifungals available to treat fungal infections. Azoles function by targeting t...

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Detalles Bibliográficos
Autores principales: Mount, Harley O’Connor, Revie, Nicole M., Todd, Robert T., Anstett, Kaitlin, Collins, Cathy, Costanzo, Michael, Boone, Charles, Robbins, Nicole, Selmecki, Anna, Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922528/
https://www.ncbi.nlm.nih.gov/pubmed/29702647
http://dx.doi.org/10.1371/journal.pgen.1007319