Performance of next-generation sequencing on small tumor specimens and/or low tumor content samples using a commercially available platform

BACKGROUND: Next generation sequencing tests (NGS) are usually performed on relatively small core biopsy or fine needle aspiration (FNA) samples. Data is limited on what amount of tumor by volume or minimum number of FNA passes are needed to yield sufficient material for running NGS. We sought to id...

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Detalles Bibliográficos
Autores principales: Morris, Scott, Subramanian, Janakiraman, Gel, Esma, Runger, George, Thompson, Eric, Mallery, David, Weiss, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922576/
https://www.ncbi.nlm.nih.gov/pubmed/29702695
http://dx.doi.org/10.1371/journal.pone.0196556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922576/
https://www.ncbi.nlm.nih.gov/pubmed/29702695
http://dx.doi.org/10.1371/journal.pone.0196556

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