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On the role of extrinsic noise in microRNA-mediated bimodal gene expression

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Bimodal distributions of gene expression levels provide experimental evidence of phenotypic differentiation, where the modes of the distribution often correspond to...

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Detalles Bibliográficos
Autores principales: Del Giudice, Marco, Bo, Stefano, Grigolon, Silvia, Bosia, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922620/
https://www.ncbi.nlm.nih.gov/pubmed/29664903
http://dx.doi.org/10.1371/journal.pcbi.1006063