CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation

We have previously shown that an Epoxyeicosatrienoic Acid (EET) -agonist has pleiotropic effects and reverses cardiomyopathy by decreasing inflammatory molecules and increasing antioxidant signaling. We hypothesized that administration of an EET agonist would increase Peroxisome proliferator-activat...

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Detalles Bibliográficos
Autores principales: Singh, SP, McClung, JA, Bellner, L, Cao, J, Waldman, M, Schragenheim, J, Arad, M, Hochhauser, E, Falck, JR, Weingarten, JA, Peterson, SJ, Abraham, NG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922773/
https://www.ncbi.nlm.nih.gov/pubmed/29707604
http://dx.doi.org/10.4172/2329-6607.1000233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922773/
https://www.ncbi.nlm.nih.gov/pubmed/29707604
http://dx.doi.org/10.4172/2329-6607.1000233

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