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CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy via PGC-1 α Activation
We have previously shown that an Epoxyeicosatrienoic Acid (EET) -agonist has pleiotropic effects and reverses cardiomyopathy by decreasing inflammatory molecules and increasing antioxidant signaling. We hypothesized that administration of an EET agonist would increase Peroxisome proliferator-activat...
Autores principales: | Singh, SP, McClung, JA, Bellner, L, Cao, J, Waldman, M, Schragenheim, J, Arad, M, Hochhauser, E, Falck, JR, Weingarten, JA, Peterson, SJ, Abraham, NG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922773/ https://www.ncbi.nlm.nih.gov/pubmed/29707604 http://dx.doi.org/10.4172/2329-6607.1000233 |
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