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Hydrogel microenvironments for cancer spheroid growth and drug screening

Multicellular cancer spheroids (MCSs) have emerged as a promising in vitro model that replicates many features of solid tumors in vivo. Biomimetic hydrogel scaffolds for MCS growth offer a broad spectrum of biophysical and biochemical cues that help to recapitulate the behavior of natural extracellu...

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Detalles Bibliográficos
Autores principales: Li, Yunfeng, Kumacheva, Eugenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922799/
https://www.ncbi.nlm.nih.gov/pubmed/29719868
http://dx.doi.org/10.1126/sciadv.aas8998