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Sodium chloride exacerbates dextran sulfate sodium-induced colitis by tuning proinflammatory and antiinflammatory lamina propria mononuclear cells through p38/MAPK pathway in mice

AIM: To investigate the influence of high salt on dextran sulfate sodium (DSS)-induced colitis in mice and explore the underlying mechanisms of this effect. METHODS: DSS and NaCl were used to establish the proinflammatory animal model. We evaluated the colitis severity. Flow cytometry was employed f...

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Detalles Bibliográficos
Autores principales: Guo, Hong-Xia, Ye, Nan, Yan, Ping, Qiu, Min-Yue, Zhang, Ji, Shen, Zi-Gang, He, Hai-Yang, Tian, Zhi-Qiang, Li, Hong-Li, Li, Jin-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922996/
https://www.ncbi.nlm.nih.gov/pubmed/29713131
http://dx.doi.org/10.3748/wjg.v24.i16.1779