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High-grade serous carcinoma with discordant p53 signature: report of a case with new insight regarding high-grade serous carcinogenesis

BACKGROUND: Although p53 signature, benign-appearing epithelial cells with p53 diffuse expression, is frequently found in the fallopian tubes, the clinical and pathological significance of this lesion in the case of high-grade serous carcinoma (HGSC) patients still remains unclear. CASE PRESENTATION...

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Detalles Bibliográficos
Autores principales: Hatano, Yuichiro, Fukuda, Shinya, Makino, Hiroshi, Tomita, Hiroyuki, Morishige, Ken-ichirou, Hara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923005/
https://www.ncbi.nlm.nih.gov/pubmed/29703236
http://dx.doi.org/10.1186/s13000-018-0702-3