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Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells

BACKGROUND: Since tumor growth requires reactivation of telomerase (hTERT), this enzyme is a challenging target for drug development. Therefore, it is of great interest to identify telomerase expression and activity regulators. Retinoids are well-known inducers of granulocytic maturation associated...

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Detalles Bibliográficos
Autores principales: El Hajj, Joëlle, Nguyen, Eric, Liu, Qingyuan, Bouyer, Claire, Adriaenssens, Eric, Hilal, George, Ségal-Bendirdjian, Evelyne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923027/
https://www.ncbi.nlm.nih.gov/pubmed/29703210
http://dx.doi.org/10.1186/s12943-018-0835-8