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Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells
BACKGROUND: Since tumor growth requires reactivation of telomerase (hTERT), this enzyme is a challenging target for drug development. Therefore, it is of great interest to identify telomerase expression and activity regulators. Retinoids are well-known inducers of granulocytic maturation associated...
Autores principales: | El Hajj, Joëlle, Nguyen, Eric, Liu, Qingyuan, Bouyer, Claire, Adriaenssens, Eric, Hilal, George, Ségal-Bendirdjian, Evelyne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923027/ https://www.ncbi.nlm.nih.gov/pubmed/29703210 http://dx.doi.org/10.1186/s12943-018-0835-8 |
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