Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis

Mycobacterium tuberculosis kills more people than any other bacterial pathogen and is becoming increasingly untreatable due to the emergence of resistance. Verapamil, an FDA-approved calcium channel blocker, potentiates the effect of several antituberculosis (anti-TB) drugs in vitro and in vivo. Thi...

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Detalles Bibliográficos
Autores principales: Chen, Chao, Gardete, Susana, Jansen, Robert Sander, Shetty, Annanya, Dick, Thomas, Rhee, Kyu Y., Dartois, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923092/
https://www.ncbi.nlm.nih.gov/pubmed/29463541
http://dx.doi.org/10.1128/AAC.02107-17