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Acylhydrazones as Antifungal Agents Targeting the Synthesis of Fungal Sphingolipids

The incidence of invasive fungal infections has risen dramatically in recent decades. Current antifungal drugs are either toxic, likely to interact with other drugs, have a narrow spectrum of activity, or induce fungal resistance. Hence, there is a great need for new antifungals, possibly with novel...

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Detalles Bibliográficos
Autores principales: Lazzarini, Cristina, Haranahalli, Krupanandan, Rieger, Robert, Ananthula, Hari Krishna, Desai, Pankaj B., Ashbaugh, Alan, Linke, Michael J., Cushion, Melanie T., Ruzsicska, Bela, Haley, John, Ojima, Iwao, Del Poeta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923120/
https://www.ncbi.nlm.nih.gov/pubmed/29507066
http://dx.doi.org/10.1128/AAC.00156-18