Novel Zinc-Attenuating Compounds as Potent Broad-Spectrum Antifungal Agents with In Vitro and In Vivo Efficacy

An increase in the incidence of rare but hard-to-treat invasive fungal pathogens as well as resistance to the currently available antifungal drugs calls for new broad-spectrum antifungals with a novel mechanism of action. Here we report the identification and characterization of two novel zinc-atten...

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Detalles Bibliográficos
Autores principales: Cohrt, Karen A. O'Hanlon, Marín, Laura, Kjellerup, Lasse, Clausen, Johannes D., Dalby-Brown, William, Calera, José Antonio, Winther, Anne-Marie Lund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923171/
https://www.ncbi.nlm.nih.gov/pubmed/29439980
http://dx.doi.org/10.1128/AAC.02024-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923171/
https://www.ncbi.nlm.nih.gov/pubmed/29439980
http://dx.doi.org/10.1128/AAC.02024-17

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