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Novel Zinc-Attenuating Compounds as Potent Broad-Spectrum Antifungal Agents with In Vitro and In Vivo Efficacy
An increase in the incidence of rare but hard-to-treat invasive fungal pathogens as well as resistance to the currently available antifungal drugs calls for new broad-spectrum antifungals with a novel mechanism of action. Here we report the identification and characterization of two novel zinc-atten...
Autores principales: | Cohrt, Karen A. O'Hanlon, Marín, Laura, Kjellerup, Lasse, Clausen, Johannes D., Dalby-Brown, William, Calera, José Antonio, Winther, Anne-Marie Lund |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923171/ https://www.ncbi.nlm.nih.gov/pubmed/29439980 http://dx.doi.org/10.1128/AAC.02024-17 |
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