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Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria

Sulfadoxine-pyrimethamine with amodiaquine is recommended by the World Health Organization as seasonal malaria chemoprevention for children aged 3 to 59 months in the sub-Sahel regions of Africa. Suboptimal dosing in children may lead to treatment failure and increased resistance. Pooled individual...

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Detalles Bibliográficos
Autores principales: de Kock, Miné, Tarning, Joel, Workman, Lesley, Allen, Elizabeth N., Tekete, Mamadou M., Djimde, Abdoulaye A., Bell, David J., Ward, Steve A., Barnes, Karen I., Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923181/
https://www.ncbi.nlm.nih.gov/pubmed/29463542
http://dx.doi.org/10.1128/AAC.01370-17