Human rhinovirus internal ribosome entry site element enhances transgene expression in transfected CHO-S cells

Chinese hamster ovary (CHO) cells are mainly used for recombinant protein production. However, the unstable transgene expression and lower transgene copy numbers are the major issues need to be resolved. Here, eleven internal ribosome entry site (IRES) elements from viral and cellular IRES were eval...

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Detalles Bibliográficos
Autores principales: Chai, Yu-rong, Ge, Meng-meng, Wei, Ting-ting, Jia, Yan-long, Guo, Xiao, Wang, Tian-yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923211/
https://www.ncbi.nlm.nih.gov/pubmed/29703950
http://dx.doi.org/10.1038/s41598-018-25049-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923211/
https://www.ncbi.nlm.nih.gov/pubmed/29703950
http://dx.doi.org/10.1038/s41598-018-25049-9

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