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TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth
Acetylation of microtubules (MT) confers mechanical stability necessary for numerous functions including cell cycle and intracellular transport. Although αTAT1 is a major MT acetyltransferase, how this enzyme is regulated remains much less clear. Here we report TGF-β-activated kinase 1 (TAK1) as a k...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923212/ https://www.ncbi.nlm.nih.gov/pubmed/29703898 http://dx.doi.org/10.1038/s41467-018-04121-y |