Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

Snail is a major transcriptional factor that induces epithelial-mesenchymal transition (EMT). In this study, we explore the effect of Snail on tumor immunity. Snail knockdown in mouse ovarian cancer cells suppresses tumor growth in immunocompetent mice, associated with an increase of CD8(+) tumor-in...

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Detalles Bibliográficos
Autores principales: Taki, Mana, Abiko, Kaoru, Baba, Tsukasa, Hamanishi, Junzo, Yamaguchi, Ken, Murakami, Ryusuke, Yamanoi, Koji, Horikawa, Naoki, Hosoe, Yuko, Nakamura, Eijiro, Sugiyama, Aiko, Mandai, Masaki, Konishi, Ikuo, Matsumura, Noriomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923228/
https://www.ncbi.nlm.nih.gov/pubmed/29703902
http://dx.doi.org/10.1038/s41467-018-03966-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923228/
https://www.ncbi.nlm.nih.gov/pubmed/29703902
http://dx.doi.org/10.1038/s41467-018-03966-7

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