Deconvolution of subcellular protrusion heterogeneity and the underlying actin regulator dynamics from live cell imaging

Cell protrusion is morphodynamically heterogeneous at the subcellular level. However, the mechanism of cell protrusion has been understood based on the ensemble average of actin regulator dynamics. Here, we establish a computational framework called HACKS (deconvolution of heterogeneous activity in...

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Detalles Bibliográficos
Autores principales: Wang, Chuangqi, Choi, Hee June, Kim, Sung-Jin, Desai, Aesha, Lee, Namgyu, Kim, Dohoon, Bae, Yongho, Lee, Kwonmoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923236/
https://www.ncbi.nlm.nih.gov/pubmed/29703977
http://dx.doi.org/10.1038/s41467-018-04030-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923236/
https://www.ncbi.nlm.nih.gov/pubmed/29703977
http://dx.doi.org/10.1038/s41467-018-04030-0

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