Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary cholangitis

Pruritus is a common complication of cholestatic liver diseases. Inhibition of the ileal bile acid transporter (IBAT/ASBT) may emerge as treatment option. Our aim was to assess tolerability and effect on pruritus of the selective IBAT inhibitor A4250 in patients with primary biliary cholangitis (PBC...

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Detalles Bibliográficos
Autores principales: Al-Dury, Samer, Wahlström, Annika, Wahlin, Staffan, Langedijk, Jacqueline, Elferink, Ronald Oude, Ståhlman, Marcus, Marschall, Hanns-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923243/
https://www.ncbi.nlm.nih.gov/pubmed/29704003
http://dx.doi.org/10.1038/s41598-018-25214-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923243/
https://www.ncbi.nlm.nih.gov/pubmed/29704003
http://dx.doi.org/10.1038/s41598-018-25214-0

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