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Interaction of the primordial germ cell-specific protein C2EIP with PTCH2 directs differentiation of embryonic stem cells via HH signaling activation

Although many marker genes for germ cell differentiation have been identified, genes that specifically regulate primordial germ cell (PGC) generation are more difficult to determine. In the current study, we confirmed that C2EIP is a PGC marker gene that regulates differentiation by influencing the...

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Detalles Bibliográficos
Autores principales: Zuo, Qisheng, Jin, Kai, Song, Jiuzhou, Zhang, Yani, Chen, Guohong, Li, Bichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923244/
https://www.ncbi.nlm.nih.gov/pubmed/29703892
http://dx.doi.org/10.1038/s41419-018-0557-2