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Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression

Necroptosis, a form of regulated necrotic cell death, is mediated by receptor interacting protein 1 (RIPK1), RIPK3, and mixed lineage kinase domain-like protein (MLKL). However, the mechanism by which necroptosis promotes inflammation is still unclear. Here we report that the expression of cytokines...

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Detalles Bibliográficos
Autores principales: Zhu, Kezhou, Liang, Wei, Ma, Zaijun, Xu, Daichao, Cao, Shuangyi, Lu, Xiaojuan, Liu, Nan, Shan, Bing, Qian, Lihui, Yuan, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923285/
https://www.ncbi.nlm.nih.gov/pubmed/29703889
http://dx.doi.org/10.1038/s41419-018-0524-y