Application of droplet digital PCR in the analysis of genome integration and organization of the transgene in BAC transgenic mice

Transgenic (Tg) mice containing bacterial artificial chromosome (BAC) DNA are widely used for gene expression analysis and gene therapy models because BAC transgenes provide gene expression at physiological levels with the same developmental timing as endogenous genes. To ensure correct interpretati...

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Detalles Bibliográficos
Autores principales: Nakagaki, Ayumi, Urakawa, Asuka, Hirano, Shiori, Anami, Takeru, Kishino, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923295/
https://www.ncbi.nlm.nih.gov/pubmed/29703985
http://dx.doi.org/10.1038/s41598-018-25001-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923295/
https://www.ncbi.nlm.nih.gov/pubmed/29703985
http://dx.doi.org/10.1038/s41598-018-25001-x

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