Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding

Botulinum neurotoxins (BoNTs) are a family of highly dangerous bacterial toxins, with seven major serotypes (BoNT/A-G). Members of BoNTs, BoNT/A1 and BoNT/B1, have been utilized to treat an increasing number of medical conditions. The clinical trials are ongoing for BoNT/A2, another subtype of BoNT/...

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Detalles Bibliográficos
Autores principales: Gustafsson, Robert, Zhang, Sicai, Masuyer, Geoffrey, Dong, Min, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923319/
https://www.ncbi.nlm.nih.gov/pubmed/29649119
http://dx.doi.org/10.3390/toxins10040153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923319/
https://www.ncbi.nlm.nih.gov/pubmed/29649119
http://dx.doi.org/10.3390/toxins10040153

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