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Bavachinin Induces Oxidative Damage in HepaRG Cells through p38/JNK MAPK Pathways

Drug-induced liver injury is one of the main causes of drug non-approval and drug withdrawal by the Food and Drug Administration (FDA). Bavachinin (BVC) is a natural product derived from the fruit of the traditional Chinese herb Fructus Psoraleae (FP). There have been reports of acute liver injury f...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Wang, Min, Tian, Yu, Sun, Xiao, Sun, Guibo, Sun, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923320/
https://www.ncbi.nlm.nih.gov/pubmed/29649125
http://dx.doi.org/10.3390/toxins10040154