EBV(+) and MSI Gastric Cancers Harbor High PD-L1/PD-1 Expression and High CD8(+) Intratumoral Lymphocytes

Both EBV(+) and MSI gastric cancers (GCs) have high lymphoid infiltration which is rare in MSS/EBV(−) cancers. PD-L1/PD-1 interaction leads to a down-regulated immune response and it is one of the most promising targets for gastric cancer immunotherapy. PD-L1/PD-1 and CD8 expression were immunohisto...

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Detalles Bibliográficos
Autores principales: De Rosa, Simona, Sahnane, Nora, Tibiletti, Maria Grazia, Magnoli, Francesca, Vanoli, Alessandro, Sessa, Fausto, Chiaravalli, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923357/
https://www.ncbi.nlm.nih.gov/pubmed/29614789
http://dx.doi.org/10.3390/cancers10040102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923357/
https://www.ncbi.nlm.nih.gov/pubmed/29614789
http://dx.doi.org/10.3390/cancers10040102

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