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EBV(+) and MSI Gastric Cancers Harbor High PD-L1/PD-1 Expression and High CD8(+) Intratumoral Lymphocytes
Both EBV(+) and MSI gastric cancers (GCs) have high lymphoid infiltration which is rare in MSS/EBV(−) cancers. PD-L1/PD-1 interaction leads to a down-regulated immune response and it is one of the most promising targets for gastric cancer immunotherapy. PD-L1/PD-1 and CD8 expression were immunohisto...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923357/ https://www.ncbi.nlm.nih.gov/pubmed/29614789 http://dx.doi.org/10.3390/cancers10040102 |