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EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

The presence of the Epstein-Barr virus (EBV)-encoded nuclear antigen-1 (EBNA1) protein in all EBV-carrying tumours constitutes a marker that distinguishes the virus-associated cancer cells from normal cells and thereby offers opportunities for targeted therapeutic intervention. EBNA1 is essential fo...

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Detalles Bibliográficos
Autores principales: Wilson, Joanna B., Manet, Evelyne, Gruffat, Henri, Busson, Pierre, Blondel, Marc, Fahraeus, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923364/
https://www.ncbi.nlm.nih.gov/pubmed/29642420
http://dx.doi.org/10.3390/cancers10040109