Roles of Polyploid/Multinucleated Giant Cancer Cells in Metastasis and Disease Relapse Following Anticancer Treatment

Tumors and tumor-derived cell lines contain polyploid giant cells with significantly elevated genomic content, often with multiple nuclei. The frequency of giant cells can increase markedly following anticancer treatment. Although giant cells enter a dormant phase and therefore do not form macroscop...

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Detalles Bibliográficos
Autores principales: Mirzayans, Razmik, Andrais, Bonnie, Murray, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923373/
https://www.ncbi.nlm.nih.gov/pubmed/29662021
http://dx.doi.org/10.3390/cancers10040118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923373/
https://www.ncbi.nlm.nih.gov/pubmed/29662021
http://dx.doi.org/10.3390/cancers10040118

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