Responses to the Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor Tirabrutinib (ONO/GS-4059) in Diffuse Large B-cell Lymphoma Cell Lines

Bruton’s tyrosine kinase (BTK) is a key regulator of the B-cell receptor signaling pathway, and aberrant B-cell receptor (BCR) signaling has been implicated in the survival of malignant B-cells. However, responses of the diffuse large B-cell lymphoma (DLBCL) to inhibitors of BTK (BTKi) are infrequen...

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Detalles Bibliográficos
Autores principales: Kozaki, Ryohei, Vogler, Meike, Walter, Harriet S., Jayne, Sandrine, Dinsdale, David, Siebert, Reiner, Dyer, Martin J.S., Yoshizawa, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923382/
https://www.ncbi.nlm.nih.gov/pubmed/29690649
http://dx.doi.org/10.3390/cancers10040127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923382/
https://www.ncbi.nlm.nih.gov/pubmed/29690649
http://dx.doi.org/10.3390/cancers10040127

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