7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway

The 7-Acetylsinumaximol B (7-AB), a bioactive cembranoid, was originally discovered from aquaculture soft coral Sinularia sandensis. The current study investigated the anti-proliferative property of 7-AB towards the NCI-N87 human gastric cancer cell line. An MTT cell proliferative assay was applied...

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Detalles Bibliográficos
Autores principales: Tsai, Tsung-Chang, Lai, Kuei-Hung, Su, Jui-Hsin, Wu, Yu-Jen, Sheu, Jyh-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923391/
https://www.ncbi.nlm.nih.gov/pubmed/29587440
http://dx.doi.org/10.3390/md16040104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923391/
https://www.ncbi.nlm.nih.gov/pubmed/29587440
http://dx.doi.org/10.3390/md16040104

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