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7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway
The 7-Acetylsinumaximol B (7-AB), a bioactive cembranoid, was originally discovered from aquaculture soft coral Sinularia sandensis. The current study investigated the anti-proliferative property of 7-AB towards the NCI-N87 human gastric cancer cell line. An MTT cell proliferative assay was applied...
Autores principales: | Tsai, Tsung-Chang, Lai, Kuei-Hung, Su, Jui-Hsin, Wu, Yu-Jen, Sheu, Jyh-Horng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923391/ https://www.ncbi.nlm.nih.gov/pubmed/29587440 http://dx.doi.org/10.3390/md16040104 |
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