Applying Unique Molecular Identifiers in Next Generation Sequencing Reveals a Constrained Viral Quasispecies Evolution under Cross-Reactive Antibody Pressure Targeting Long Alpha Helix of Hemagglutinin

To overcome yearly efforts and costs for the production of seasonal influenza vaccines, new approaches for the induction of broadly protective and long-lasting immune responses have been developed in the past decade. To warrant safety and efficacy of the emerging crossreactive vaccine candidates, it...

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Detalles Bibliográficos
Autores principales: Hauck, Nastasja C., Kirpach, Josiane, Kiefer, Christina, Farinelle, Sophie, Maucourant, Sophie, Morris, Stephen A., Rosenberg, William, He, Feng Q., Muller, Claude P., Lu, I-Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923442/
https://www.ncbi.nlm.nih.gov/pubmed/29587397
http://dx.doi.org/10.3390/v10040148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923442/
https://www.ncbi.nlm.nih.gov/pubmed/29587397
http://dx.doi.org/10.3390/v10040148

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