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Cytoplasmic Translocation of Nucleolar Protein NOP53 Promotes Viral Replication by Suppressing Host Defense

NOP53 is a tumor suppressor protein located in the nucleolus and is translocated to the cytoplasm during infection by vesicular stomatitis virus (VSV) and herpes simplex virus type 1 (HSV-1), as shown in our previous study. Cytoplasmic NOP53 interacts with the retinoic acid-inducible gene I (RIG-I)...

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Detalles Bibliográficos
Autores principales: Meng, Wen, Han, Shi-Chong, Li, Cui-Cui, Dong, Hui-Jun, Chang, Jian-Yu, Wang, Hwa-Chain Robert, Wang, Xiao-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923502/
https://www.ncbi.nlm.nih.gov/pubmed/29677136
http://dx.doi.org/10.3390/v10040208