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Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity

Nucleoside analogs have been frequently identified as antiviral agents. In recent years, gemcitabine, a cytidine analog in clinical use for the treatment of many solid tumors, was also shown to have antiviral activity against a broad range of viruses. Nucleoside analogs generally interfere with cell...

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Detalles Bibliográficos
Autores principales: Shin, Hye Jin, Kim, Chonsaeng, Cho, Sungchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923505/
https://www.ncbi.nlm.nih.gov/pubmed/29677162
http://dx.doi.org/10.3390/v10040211