Cargando…

Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response

Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus. Mechanoadaptation can be restored to aged bone...

Descripción completa

Detalles Bibliográficos
Autores principales: Javaheri, Behzad, Carriero, Alessandra, Wood, Maria, De Souza, Roberto, Lee, Peter D., Shefelbine, Sandra, Pitsillides, Andrew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924380/
https://www.ncbi.nlm.nih.gov/pubmed/29703931
http://dx.doi.org/10.1038/s41598-018-25084-6