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Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response
Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus. Mechanoadaptation can be restored to aged bone...
Autores principales: | Javaheri, Behzad, Carriero, Alessandra, Wood, Maria, De Souza, Roberto, Lee, Peter D., Shefelbine, Sandra, Pitsillides, Andrew A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924380/ https://www.ncbi.nlm.nih.gov/pubmed/29703931 http://dx.doi.org/10.1038/s41598-018-25084-6 |
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